Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 54274056 | HCID 54274056 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 54218971 | HCID 54218971 | — |
Reaction Steps
The compound (19-a) (0.288 g) was dissolved in the solvent mixture (acetic acid:water:THF=4:2:1) (30 ml), and the solution was maintained at 45° C. for 3.5 hours. The crude product obtained by the conventional treatment of the reaction mixture was purified on silica gel column to give the titled compound (20-a) (yield:0.184 g (76%)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06242485B1 |
|---|
| Source dataset | uspto-grants-2001_06 |
|---|
| ORD ID | ord-ecd68d295ebb42e1a0757ca6df5be839 |
|---|
| Source note | uspto-grants-2001_06 |
|---|
