benzyl (2S)-2-aminopropanoate → HCID 70879933, compound

Participants

Reaction Steps

The product of example 20A and L-alanine benzyl ester were processed as in examples 1E to yield (2RS,3R)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-cyclohexyl)butanoyl-L-alanine benzyl ester. 0.5 g of the above product was hydrogenated in 2 mL of isopropyl alcohol in the presence of 20 mg of 10%-palladium on charcoal to yield (2RS,3R)-3-(tert-butoxycarbonylamino)-2-hydroxy-4-cyclohexyl)butanoyl-L-alanine (0.4 g).

Provenance & Evidence