HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridineacetic acid → HCID 10815603, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridineacetic acid | HCID 108 | — |
| Reactant | 4-Pyridineacetic acid | HCID 34228 | — |
| Reactant | HCID 5255691 | HCID 5255691 | — |
| Reactant | HCID 22621952 | HCID 22621952 | — |
| Product | HCID 10815603 | HCID 10815603 | 95% |
Reaction Steps
By substituting in Example 75, 3-bromo-8-chloro-11-(1-piperazinyl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (0.32 g, 0.81 mmoles) (Preparative Example 40) for 8-chloro-11-(1-piperazinyl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine and 3-pyridylacetic acid (0.117 g, 0.86 mmoles) for 4-pyridylacetic acid and using the method described in Example 75, one obtains the title compound (0.3942 g, 95%, MH+511).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242458B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-d99eda7baf6248c2b8978131093b4a35 |
| Source note | uspto-grants-2001_06 |