HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridineacetic acid → HCID 10719054, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridineacetic acid | HCID 108 | — |
| Reactant | 4-Pyridineacetic acid | HCID 34228 | — |
| Reactant | HCID 5255691 | HCID 5255691 | — |
| Reactant | HCID 10760108 | HCID 10760108 | — |
| Product | HCID 10719054 | HCID 10719054 | 88.8% |
Reaction Steps
By substituting in Example 75, 4,8-chloro-11-(1-piperazinyl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine (0.3 g, 0.86 mmoles) (Preparative Example 41) for 8-chloro-11-(1-piperazinyl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine and 3-pyridylacetic acid (0.1181 g, 0.86 mmoles) for 4-pyridylacetic acid and using the method described in Example 75, one obtains the title compound (0.357 g, 88%, MH+467).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242458B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-3bd486780222447495ff1abd690d8ad8 |
| Source note | uspto-grants-2001_06 |