(Naphthalen-2-yl)boronic acid → HCID 131722607, compound

HRID 1066354Notes

Reaction equation

HRID 1066354 reaction equation
Br[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1/[CH:9]=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12].[CH:16]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH:19]=[CH:18][C:17]=1B(O)O>>[CH:24]1[C:25]2[C:20](=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:21]=[CH:22][C:23]=1[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1/[CH:9]=[CH:10]/[C:11]([O:13][CH2:14][CH3:15])=[O:12]

Participants

3

Reactant 2

HCID 2734375(Naphthalen-2-yl)boronic acidHCID 11043787HCID 11043787, compound

Product 1

HCID 131722607HCID 131722607, compound

Procedure

The benzyl bromide (500 mg) of example 1, step 2 was treated with 2-naphthylboronic acid according to the same procedure previously described to yield 360 mg of the title compound.

Sources & evidence

ORD record
ord-bd742ce9927545239710e3219353b9d1
Source dataset
uspto-grants-2001_06
Patent number
US06242493B1

Reaction notes

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