Hydrochloric Acid → HCID 21199940, compound

Participants

Reaction Steps

3,4-Diaminothiophene (2.0 g, 17 mmol) was dissolved in pyridine and the solution was added dropwise to a stirred solution of 6.5 g (34 mmol) of decanoyl chloride (boiling point 125° C. at 45 mbar) via a syringe. It was stirred overnight. The reaction mixture was poured into ice water mixed with concentrated hydrochloric acid and extracted with chloroform. The organic layers were washed with water, 2% strength NaOH and again with water and then dried over MgSO4 which was mixed with active carbon to remove the colored impurities. After evaporating the solvent, a solid was obtained which was recrystallized from a toluene-hexane mixture. The solid had a melting point of 99-100° C. The yield was 6.7 g (90% of theory).

Provenance & Evidence