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HRID1066413

反应详情

EQUATION

反应方程式

HRID 1066413 的结构方程式

REACTANTS

反应物

3
结构：Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
HCID60961

Adenosine

C10H13N5O4

结构：Nc1nc(N)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3OCCCCn3ccnc3)c2n1
HCID22874735

未命名化合物

结构：Nc1nc(N)c2ncn([C@@H]3O[C@H](CO)[C@](O)(CCCCn4ccnc4)[C@H]3O)c2n1
HCID86756992

未命名化合物

PRODUCTS

生成物

1
结构：Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2OCCCCn2ccnc2)c(=O)[nH]1
HCID136079785

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CS(C)=O
溶剂HCID679

Dimethyl sulfoxide

C2H6OS

PROCEDURE

实验过程

A mixture of the 2,6-diamino-9-[2′-O-(imidazol-1-yl)butyl-β-D-ribofuranosyl]purine and 2,6-diamino-9-[3′-(imidazol-1-yl)butyl-β-D-ribofuranosyl]purine isomers in 0.1 M tris buffer (pH 7.4), 0.1 M NaSO4 buffer (pH 7.4) and DMSO is treated with adenosine deaminase at RT for 5 days as per the procedure of Example 3. The product containing fractions are purified by silica gel chromatography and the product containing fraction evaporated to give the product.

WORKUP

后处理

  1. additionThe product containing fractions
  2. customare purified by silica gel chromatography
  3. additionthe product containing fraction
  4. customevaporated
  5. customto give the product