反应详情

As per the procedure of Example 49, uridine (8.5 g) as treated with dibutyl tin oxide (8.2 g, 1 eq). The resulting 2′,3′-O-dibutylstannylene uridine was treated with iodomethane (16 ml) at 42° C. as per Example 50 to give a mixture of the 2′ and 3′ alkylated products (3.5 g) as a foam.

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