HuagongsheHuagongshe Chemistry Print Report · For research reference only
Uridine → 2'-O-Nonyluridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Uridine | HCID 6029 | — |
| Reactant | 1-Iodononane | HCID 20275 | — |
| Reactant | Dibutyltin oxide | HCID 61221 | — |
| Reactant | 2',3'-O-dibutylstannyleneuridine | HCID 131720090 | — |
| Product | 2'-O-Nonyluridine | HCID 22874743 | — |
Reaction Steps
As per the procedure of Example 49, uridine (22.5 g) was treated with dibutyl tin oxide (22.5 g, 1 eq). The resulting 2′,3′-O-dibutylstannyleneuridine was treated with iodononane (11 ml, 1.3 eq.) at 130-140° C. as per Example 50 to give the 2′ and 3′ isomers (11.2 g) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242592B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-bd8bdd08661d485ebc9d527d46ba1bd5 |
| Source note | uspto-grants-2001_06 |