HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cytidine → 2'-O-Pentylcytidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cytidine | HCID 6175 | — |
| Reactant | 1-Bromopentane | HCID 8057 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2'-O-Pentylcytidine | HCID 15484895 | — |
Reaction Steps
Cytidine (10 g, 0.041 mol), sodium hydride (2.4 g, 1.5 eq), bromopentane (7.6 ml, 1.5 eq.) in DMSO (90 ml) were reacted as per the procedure of Example 71, Step 1 to yield the 2′ and 3′ isomers as a foam (7.6 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242592B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-bdbd6fa57ff94b5a9c76c48876300bd6 |
| Source note | uspto-grants-2001_06 |