1-Propanol → HCID 178458112, compound

Participants

Reaction Conditions

Reaction Steps

A 500 mL round-bottomed flask fitted with a condenser, a magnetic stirrer and a nitrogen atmosphere is charged with 5.48 g (0.0169 mol) of 4,6-bis-(2,4-dimethylphenyl-2-chloro-s-triazine, 10.2 g (0.169 mol) of n-propanol, 2,37 g (0.0246 mol) of methane-sulfonic acid and 25 mL of m-xylene. The mixture is stirred at 90° C. for one hour. The mixture is then allowed to cool to room temperature and vacuum filtered through a plug of silica gel which is subsequently washed with 95:5 heptane:ethyl acetate. The combined organic layers are vacuum filtered through another plug of silica gel. The solvent is removed under reduced pressure to afford 3.31 g of the title compound as off-white crystals melting at 86-88° C.

Provenance & Evidence