反应详情

Methyl 2-benzylidene-3-hydroxypropionate (847.2 mg, 4.408 mmols) was dissolved in 8 ml of methanol, and 21.7 mg (water content 2.7%) of 5% palladium-carbon were added thereto to conduct catalytic reduction in a hydrogen atmosphere for 140 minutes. After the completion of the reaction, the reaction solution was filtered with Celite to remove the palladium-carbon. The resulting solution was concentrated under reduced pressure to obtain 849.2 mg of a crude product of the above title compound.

1. customfor 140 minutes
2. customAfter the completion of the reaction
3. filtrationthe reaction solution was filtered with Celite
4. customto remove the palladium-carbon
5. concentrationThe resulting solution was concentrated under reduced pressure