反应详情

Under an atmosphere of argon 11.36 g of 3-benzyloxybenzamide were suspended in CH2Cl2 (200 ml) and 9.5 g triethyloxonium fluoroborate in CH2Cl2 (100 ml) were added dropwise on ice cooling. The reaction mixture was then stirred further 20 h at RT until completion of reaction according to TLC analysis (CH2Cl2/MeOH: 15/1). The solid which had formed was filtered off, washed with ether to give the desired ethyl m-benzyloxybenzimidate tetrafluoroborate as white crystals, mp 152°-154° C., which was used without further purification in the next step.

1. customThe solid which had formed
2. filtrationwas filtered off
3. washwashed with ether