HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 4'-Decyloxybiphenyl-4-ylethyne
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-(4'-Decyloxybiphenyl-4-yl)-2-(1-hydroxy-1-methylethyl)ethyne | HCID 18328393 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4'-Decyloxybiphenyl-4-ylethyne | HCID 18328390 | — |
Reaction Steps
Compound 73 (12.90 g, 0.033 mol) and sodium hydroxide &Ovalhollow; was boiled for 1 h in toluene (100 ml) under a dry nitrogen atmosphere and the resultant toluene/acetone mixture removed in a Dean-Stark apparatus. As the toluene mixture was removed fresh toluene was added to the reaction mixture. TLC analysis (dichloromethane) revealed a complete reaction. The sodium hydroxide was filtered off and the toluene washed with water, dried (MgSO4) and removed in vacuo to leave a metallic-beige solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06242636B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-4a66eb0f025e4446b10593ebf175bcc3 |
| Source note | uspto-grants-2001_06 |