Chloroform → 3-Chloro-5-[(3-chloro-2-methoxy-6-methylpyridin-4-yl)oxy]benzonitrile

HRID 106664Notes

Reaction equation

HRID 106664 reaction equation
[Ag+2:26].[C:22](=[O:23])([O-:24])[O-:25].[CH3:20][I:21].[CH:27]([Cl:28])([Cl:29])[Cl:30].[Cl:1][c:2]1[cH:3][c:4]([C:5]#[N:6])[cH:7][c:8]([O:10][c:11]2[c:12]([Cl:19])[c:13](=[O:18])[nH:14][c:15]([CH3:17])[cH:16]2)[cH:9]1>>[Cl:1][c:2]1[cH:3][c:4]([C:5]#[N:6])[cH:7][c:8]([O:10][c:11]2[c:12]([Cl:19])[c:13]([O:18][CH3:20])[n:14][c:15]([CH3:17])[cH:16]2)[cH:9]1

Participants

6

Reactant 5

HCID 6212ChloroformHCID 6328Methyl iodideHCID 19660Carbonate IonHCID 595297553-Chloro-5-[(3-chloro-6-methyl-2-oxo-1,2-dihydropyridin-4-yl)oxy]benzonitrileHCID 178419107HCID 178419107, compound

Product 1

HCID 595297303-Chloro-5-[(3-chloro-2-methoxy-6-methylpyridin-4-yl)oxy]benzonitrile

Sources & evidence

ORD record
ord-652d627e3a1c45c69481e3c51dea9ffc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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