4-Aminobenzoic Acid → 4,4'-[(6-Chloro-1,3,5-triazine-2,4-diyl)diazanediyl]dibenzoic acid

Participants

Reaction Steps

To 350 grams of 4-aminobenzoic acid and 7437.5 grams of water at 11° C. was added a solution of 157.1 grams of cyanuric chloride in 739.93 grams of acetone and a solution of 135.2 grams of sodium carbonate in 993.5 grams of water simultaneously dropwise at a rate such that the temperature was maintained below 15° C. Following the addition the batch was allowed to mix for one hour at 15° C. and then warmed to room temperature. The solid was collected, washed with water and acetone and dried to give 335 grams of 4,4′-[(6-chloro-1,3,5-triazine-2,4-diyl)diimino]bis-benzoic acid (1) as a white/tan solid.

Provenance & Evidence