5-Chloro-2-fluorobenzaldehyde → 5-Chloro-2-fluorobenzyl alcohol

HRID 1066807Notes

Reaction equation

HRID 1066807 reaction equation
FC1C=CC(C)=CC=1CO.[F:11][C:12]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:13]=1[CH:14]=[O:15]>>[F:11][C:12]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][C:13]=1[CH2:14][OH:15]

Participants

3

Reactant 2

HCID 27735865-Chloro-2-fluorobenzaldehydeHCID 12407611(2-Fluoro-5-methylphenyl)methanol

Product 1

HCID 27736135-Chloro-2-fluorobenzyl alcohol

Procedure

The title intermediate was prepared essentially as was 2-fluoro-5-methylbenzyl alcohol, supra, except that an equimolar amount of 2-fluoro-5-chlorobenzaldehyde was employed instead of the 2-fluoro-5-methylbenzaldehyde employed therein.

Sources & evidence

ORD record
ord-9945f084e6ee4d7c8efc3743e94d4605
Source dataset
uspto-grants-2001_06
Patent number
US06245761B1

Reaction notes

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