2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 21196575, compound

Participants

Reaction Steps

A 1.00 g of 1-(2-azidoethyl)-4,5-dihydro-1H-thieno[2,3-g]indazole was dissolved in 30 ml of dioxane, 2.80 g of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone was added at room temperature, and the mixture was heated under reflux for 8 hours. The reaction mixture was cooled, poured into sodium bicarbonate aqueous solution and then extracted with chloroform. The organic layers were combined and dried with anhydrous magnesium sulfate. After removal of the drying agent by filtration, the solvent was concentrated under a reduced pressure, and the resulting residue was purified by a silica gel column chromatography to give 0.73 g of 1-(2-azidoethyl)-1H-thieno[2,3-g]indazole as a pale brown oil.

Provenance & Evidence