HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N,N-Bis(2-hydroxyethyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Diethanolamine | HCID 8113 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N,N-Bis(2-hydroxyethyl)acetamide | HCID 9793833 | — |
Reaction Steps
315 g of diethanolamine were dissolved in 500 g of tetrahydrofuran in a round-bottom flask. Then, 310 g of acetic anhydride were slowly added. The temperature was kept below 5° C. with the aid of a cooling bath. When, after the dropwise addition, exothermic heat was no longer detectable, heating was slowly carried out to 100° C. Tetrahydrofuran and acetic acid were removed under vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06245829B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-574f403e326845e38abe4a1f1b72403b |
| Source note | uspto-grants-2001_06 |