Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dibenz(b,f)azepine | HCID 9212 | — |
| Reactant | Urea hydrochloride | HCID 101721 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Carbamazepine | HCID 2554 | — |
Reaction Steps
To a suspension of urea hydrochloride (100 g, 1.036 mols) in acetic acid (125 ml), iminostilbene (25 g, 0.129 mols) was added under stirring at 25-30° C. The resulting reaction mixture was worked up according to the method of Example 1 to produce carbamazepine, which was identical to the product of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06245908B1 |
|---|
| Source dataset | uspto-grants-2001_06 |
|---|
| ORD ID | ord-8e4456a22a7f49ce952b44e08861db61 |
|---|
| Source note | uspto-grants-2001_06 |
|---|
