(2S)-2-(((tert-butoxy)carbonyl)amino)-4-phenylbutanoic acid → HCID 131722646, compound

Participants

Reaction Steps

Using Procedure D, Boc-homophenylalanine (143 mg) and Nδ-Boc-Nα-methylornithine 2-(4-methylphenyl)ethylamide (crude product from B) afforded titled product (195 mg) as a glassy solid after silica gel chromatography: 1H NMR (400 MHz, CDCl3) δ1.44 (2 s, 18H), 1.63 (m, 2H), 1.83 (m, 2H, 2.33 s, 3H), 2.63-279 (m, 7H), 3.09 (m, 2H), 3.45 (m, 2H), 4.51 (m, 1H), 4.98 (m, 1H), 7.09 (m, 4H) (m, 3H), and 7.31 (m, 2H).

Provenance & Evidence