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HRID1067077

反应详情

EQUATION

反应方程式

HRID 1067077 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)O
HCID7020908

Boc-3-(2-naphthyl)-L-alanine

C18H21NO4

结构：CN[C@@H](CCCNC(=O)OC(C)(C)C)C(=O)NCCc1ccc(O)cc1
HCID131722652

未命名化合物

PRODUCTS

生成物

1
结构：CN(C(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)OC(C)(C)C)[C@@H](CCCNC(=O)OC(C)(C)C)C(=O)NCCc1ccc(O)cc1
HCID131722653

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO.ClCCl
溶剂HCID21226129

未命名化合物

PROCEDURE

实验过程

Using Procedure B, coupling of Boc-β-(2-naphthyl)alanine and Nδ-Boc-Nα-methylornithine 2-(4-hydroxyphenyl)ethylamide, followed by silica gel chromatography (2.5% MeOH/CH2Cl2): 1H NMR (400 MHz, CDCl3) 6 1.41 (m, 21H), 1.85 (m, 1H), 2.20 (m, 2H), 2.45 (m, 1H), 2.67 (m, 4H), 3.03 (m, 4H), 4.91 (m, 2H), 6.77 (m, 2H), 6.87 (d, J=8.7 Hz, 1H), 6.98 (d, J=10.0 Hz, 1H), 7.34 (m, 1H), 7.46 (m, 2H), 7.66 (m, 1H), and 7.78 (m, 3H); mass spectrum (ES+) m/e 663 (M+1).