Trifluoroacetic acid → D-Ornithyl-N-(Phenethyl)glycine 2-Naphthylamide Trifluoroacetate

Participants

Reaction Steps

A solution of Nα,Nδ-bis-Boc-D-ornithyl-N-(phenethyl)glycine 2-naphthylamide (100 mg) and trifluoroacetic acid (10 mL) was maintained at 25° C. for 1 hr, and then concentrated in vacuo. The residue was chromatographed on a reverse-phase column (Amberchrome) with elution with acetonitrile/0.1% aqueous trifluoroacetic acid. The appropriate fractions were lyophilized to afford the titled compound (45 mg):

Provenance & Evidence