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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1067124Generated: October 30, 2026

HCID 9888387, compound → HCID 21196512, compound

https://huagongshe.com/reaction/1067124

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 9888387HCID 9888387—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 21196512HCID 2119651271.7%

Reaction Steps

3-{[2-(4,5-Diphenyloxazol-2-yl)-2-cyclopenten-1-yl]-methyl}benzamide (75 mg) was hydrogenated over 5% Pd/C (3 mg) in methanol (20 ml) at room temperature at 3 atm for 7 hours. The mixture was filtered and the filtrate was evaporated in vacuo. The residue was triturated with a mixture of ether and n-hexane to afford 3-{[2-(4,5-diphenyloxazol-2-yl)-1-cyclopentyl]methyl}benzamide (54 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06245790B1
Source datasetuspto-grants-2001_06
ORD IDord-0d7bfb1053624cd4879a43e7c37f26e0
Source noteuspto-grants-2001_06