反应详情

About 210 mg (0.62 mole) of particulate cetyl pyridinium chloride was dissolved in 50 ml of distilled water. Additionally, about 378 mg (0.62 mole) of ceftriaxone was dissolved in 50 ml of a separate volume of distilled water. Next, the ceftriaxone solution was added to the cetyl pyridinium chloride solution and stirred by a magnetic stirrer at room temperature for 1 hour forming a ceftriaxone-cetyl pyridinium chloride solution. About 400 mg of carrageenan was added to the ceftriaxone-cetyl pyridinium chloride solution and the solution was stirred by magnetic stirrer at room temperature for 2 hours. A ceftriaxone-cetyl pyridinium chloride-carrageenan hydrogel complex was formed. The complex was then freeze-dried while in the swollen state, yielding about 0.86 g of the freeze dried complex.