Potassium Hydroxide → HCID 86583767, compound

Participants

Reaction Steps

Next, 3.6 g of the 12-methoxycarbonylhexacyclo[6.6.1.13,6.110,13.02,7.09,14]heptadecene were dissolved in 30 ml of 95% ethanol, into which 1.25 g of potassium hydroxide were added. The resultant mixture was then heated under reflux. Two hours later, the reaction mixture was allowed to cool down and was then concentrated to ⅓ volume in an evaporator. Water (50 ml) and ether (50 ml) were added, and the resultant water layer was separated. When the water layer was acidified with 3% HCl, a white precipitate was formed. The precipitate was collected by filtration and was then washed with water until the washing became neutral, whereby 2.2 g of 12-carboxyhexacyclo[6.6.1.13,6.110,13.02,7.09,14]heptadecene were obtained.

Provenance & Evidence