HCID 86588919, compound → HCID 57196060, compound

Participants

Reaction Conditions

Reaction Steps

The purified protected triphosphate 22 was taken up in concentrated aqueous NH4OH (2 mL) and stirred for 3 h at approximately 48° C. The reaction mixture was concentrated to give compound 23 which was formulated with 0.1 M TEAB pH 7.0 to a concentration of 3.5 mM. The concentration and purity of the formulated bulk were confirmed by UV/Vis spectroscopy and analytical ion pair HPLC as described above, respectively. See FIG. 12.

Provenance & Evidence