HCID 21192649, compound → HCID 11783886, compound

Participants

Reaction Steps

(1E,3E)-1-Methyl-1-(3,5-dimethoxyphenyl)-2-methoxycarbonyl-3-carboxy-4-phenylbutadiene (114 g) obtained in Example 145-(1) is suspended in tert-butyl alcohol, and thereto is added potassium tert-butoxide (40.1 g), and the mixture is stirred. The reaction mixture is allowed to cool to room temperature, and further stirred for two hours. The reaction mixture is treated in the same manner as in Example 145 to give (1E,3E)-1-methyl-1-(3,5-dimethoxyphenyl)-2-methoxycarbonyl-3-carboxy-4-phenylbutadiene (the same compound as the compound of Example 135) (32 g) and (1Z,3E)-1-methyl-1-(3,5-dimethoxyphenyl)-2-methoxycarbonyl-3-carboxy-4-phenylbutadiene (the same compound as the compound of Example 121) (61.5 g).

Provenance & Evidence