HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dimethylthiophene → HCID 15895035, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dimethylthiophene | HCID 34295 | — |
| Reactant | 4-Bromobenzyl bromide | HCID 68527 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15895035 | HCID 15895035 | 60.5% |
Reaction Steps
The title compound was prepared according to the procedure in Example 5, step 1 using 2,3-dimethylthiophene (5.10 g, 45.5 mmol), 2.5M BuLi/hexanes (18.2 mL, 45.5 mmol) and 4-bromobenzyl bromide (11.4 g, 45.5 mmol) in THF. Purification on Biotage KP-Sil eluting with 100% pet ether gave 7.74 g (60%) of the title compound. 1H NMR: consistent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06248764B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-0305905230ce4e7b9b9a5340ee0dcdf4 |
| Source note | uspto-grants-2001_06 |