Benzyl Bromide → [(2-Benzylthio-8H-indeno[1,2-d]thiazol-7-yl)oxy]acetic acid

HRID 1067421노트

반응식

C([O:3][C:4](=[O:20])[CH2:5][O:6][C:7]1[C:8]2[CH2:9][C:10]3[S:14][C:13]([SH:15])=[N:12][C:11]=3[C:16]=2[CH:17]=[CH:18][CH:19]=1)C.[CH2:21](Br)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH2:21]([S:15][C:13]1[S:14][C:10]2[CH2:9][C:8]3[C:7]([O:6][CH2:5][C:4]([OH:3])=[O:20])=[CH:19][CH:18]=[CH:17][C:16]=3[C:11]=2[N:12]=1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

참가 물질

반응물 2

HCID 7498Benzyl Bromide

HCID 178472950HCID 178472950, 화합물

생성물 1

HCID 12050063[(2-Benzylthio-8H-indeno[1,2-d]thiazol-7-yl)oxy]acetic acid수율 21%

실험 절차

Using ethyl[(2-mercapto-8H-indeno[1,2-d]thiazol-7-yl)oxy]acetate and benzyl bromide, the procedure of Example 1 was otherwise repeated to synthesize the title compound. Yield 21%.

출처 및 근거

ORD 기록: ord-d3156dc7392b4f98ae34fe17bae7083c
출처 데이터셋: uspto-grants-2001_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06248766B1

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