HCID 22565374, compound → HCID 53754615, compound

HRID 1067464Notes

Reaction equation

HRID 1067464 reaction equation
C([O:3][C:4](=[O:21])[CH2:5][O:6][C:7]1[CH:20]=[CH:19][CH:18]=[C:17]2[C:8]=1[CH2:9][CH2:10][C:11]1[S:15][C:14]([SH:16])=[N:13][C:12]=12)C.[F:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[CH:29](Br)[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1[F:36]>>[F:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][C:24]=1[CH:29]([C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1[F:36])[S:16][C:14]1[S:15][C:11]2[CH2:10][CH2:9][C:8]3[C:17](=[CH:18][CH:19]=[CH:20][C:7]=3[O:6][CH2:5][C:4]([OH:3])=[O:21])[C:12]=2[N:13]=1

Participants

3

Reactant 2

HCID 22565374HCID 22565374, compoundHCID 178472952Ethyl[(2-mercapto-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy)acetate

Product 1

HCID 53754615HCID 53754615, compoundYield 58%

Procedure

Using ethyl[(2-mercapto-4,5-dihydronaphto[1,2-d]thiazol-6-yl)oxy]acetate and bis(2-fluorophenyl)methylbromide, the procedure of Example 63 was otherwise repeated to synthesize the title compound. Yield 58%.

Sources & evidence

ORD record
ord-dfcc183131a04a91a3509762c03c0bf0
Source dataset
uspto-grants-2001_06
Patent number
US06248766B1

Reaction notes

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