HCID 21193787, compound → HCID 21194016, compound

HRID 1067480Notes

Reaction equation

HRID 1067480 reaction equation
[CH2:1]([N:8](C)[C:9]1[CH:14]=[CH:13][C:12]([C:15]([CH3:33])([CH2:23][N:24]([CH3:32])[C:25]([CH2:27][C:28]([O:30][CH3:31])=[O:29])=[O:26])[C:16]([N:18]2[CH2:22][CH2:21][CH2:20][CH2:19]2)=[O:17])=[CH:11][C:10]=1[N+:34]([O-])=O)C1C=CC=CC=1>[H][H].[Pd]>[CH3:1][NH:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]([CH3:33])([CH2:23][N:24]([CH3:32])[C:25]([CH2:27][C:28]([O:30][CH3:31])=[O:29])=[O:26])[C:16]([N:18]2[CH2:22][CH2:21][CH2:20][CH2:19]2)=[O:17])=[CH:11][C:10]=1[NH2:34]

Participants

3

Reactant 1

HCID 21193787HCID 21193787, compound

Product 1

HCID 21194016HCID 21194016, compound

Reagents, catalysts & solvents 1

HCID 178506449HCID 178506449, compoundCatalyst

Procedure

Prepared analogously to Example 1d from 2-[4-(N-benzyl-methyl-amino)-3-nitro-phenyl]-2-methyl-3-(N-methoxycarbonylmethylcarbonyl-methylamino)-1-pyrrolidin-1-yl-propan-1-one and hydrogen/palladium on activated charcoal.

Sources & evidence

ORD record
ord-661a9df861864c58b022f584a197444f
Source dataset
uspto-grants-2001_06
Patent number
US06248770B1

Reaction notes

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