1-Acetoxy-2-[(3,4-methylenedioxy)-6-nitrophenyl]ethane → 1-Acetoxy-2-[(3,4-methylenedioxy)-6-aminophenyl]ethane

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Reaction Steps

The solution of 1-acetoxy-2-[(3,4-methylenedioxy)-6-nitrophenyl]ethane (0.8 g, 3.13 mmol) in ethyl acetate (25 mL) was subjected to catalytic hydrogenation using 10% palladium on carbon (100 mg) at 50 psi for 30 min. The catalyst was filtered and the solvent was removed under reduced pressure to give 1-acetoxy-2-[(3,4-methylenedioxy)-6-aminophenyl]ethane as a solid (0.69 g, 98% yield).

Provenance & Evidence