HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 2,2-bisfluoromethyl-6-nitro-2H-1-benzopyran-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 4-cyano-2,2-bisfluoromethyl-6-nitro-2H-1-benzopyran | HCID 21194980 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2,2-bisfluoromethyl-6-nitro-2H-1-benzopyran-4-carboxylic acid | HCID 21194987 | — |
Reaction Steps
A mixture of 0.93 g of 2,2-bisfluoromethyl-6-nitro-2H-1-benzopyran-4-carbonitrile, 20 ml of acetic acid, 10 ml of water and 10 ml of sulfuric acid was heated to reflux for 4.5 hours. The reaction mixture was poured Into ice water and the precipitated crystals were filtered off to give 0.83 g of 2,2-bisfluoromethyl-6-nitro-2H-1-benzopyran-4-carboxylic acid; m.p. 171-172° C.;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06248777B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-94eacf4c62c94a7e8fe438a78b4f8b2b |
| Source note | uspto-grants-2001_06 |