3-(6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yloxy)aniline → 1-{3-[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yloxy]phenyl}-3-[1-phenyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]urea

HRID 106765Notes

Reaction equation

HRID 106765 reaction equation
[CH3:26][O:27][c:28]1[cH:29][c:30]2[c:31]([O:43][c:44]3[cH:45][c:46]([NH2:47])[cH:48][cH:49][cH:50]3)[n:32][cH:33][n:34][c:35]2[cH:36][c:37]1[O:38][CH2:39][CH2:40][O:41][CH3:42].[c:1]1(-[n:7]2[n:8][c:9]([NH:16][C:17]([O:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)=[O:25])[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15])[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[n:7]2[n:8][c:9]([NH:16][C:17](=[O:25])[NH:47][c:46]3[cH:45][c:44]([O:43][c:31]4[c:30]5[cH:29][c:28]([O:27][CH3:26])[c:37]([O:38][CH2:39][CH2:40][O:41][CH3:42])[cH:36][c:35]5[n:34][cH:33][n:32]4)[cH:50][cH:49][cH:48]3)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15])[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

3

Reactant 2

HCID 668758053-(6-Methoxy-7-(2-methoxyethoxy)quinazolin-4-yloxy)anilineHCID 66898801phenyl 1-phenyl-5-(trifluoromethyl)-1H-pyrazol-3-ylcarbamate

Product 1

HCID 442429691-{3-[6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yloxy]phenyl}-3-[1-phenyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]urea

Sources & evidence

ORD record
ord-fbc8739075c0448dbdf05bece57b66b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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