2-Bromo-1-(3-nitrophenyl)ethan-1-one → HCID 178521439, compound
Reaction equation
C1(C(C2C=CC=CC=2)(C2C=CC=CC=2)[N:8]2[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][OH:16])[N:10]=[CH:9]2)C=CC=CC=1.Br[CH2:30][C:31]([C:33]1[CH:38]=[CH:37][CH:36]=[C:35]([N+:39]([O-:41])=[O:40])[CH:34]=1)=[O:32]>>[NH:8]1[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][O:16][CH2:30][C:31]([C:33]2[CH:38]=[CH:37][CH:36]=[C:35]([N+:39]([O-:41])=[O:40])[CH:34]=2)=[O:32])[N:10]=[CH:9]1Participants
3
Procedure
5 mmol of 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanol and 5 mmol of 2-bromo-1-(3-nitrophenyl)ethanone are treated as described in Example 74.
Sources & evidence
- ORD record
- ord-2186e9cc4de840a181dc3874ad14d585
- Source dataset
- uspto-grants-2001_06
- Patent number
- US06248765B1
Reaction notes
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