3-(1-Trityl-1H-imidazol-4-YL)propan-1-OL → HCID 178519717, compound

HRID 1067690Notes

Reaction equation

HRID 1067690 reaction equation
C1(C(C2C=CC=CC=2)(C2C=CC=CC=2)[N:8]2[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15]O)[N:10]=[CH:9]2)C=CC=CC=1.[OH:29][C:30]1[CH:35]=[CH:34][C:33]([C:36]([CH:38]2[CH2:43][CH2:42][CH2:41][CH2:40][CH2:39]2)=[O:37])=[CH:32][CH:31]=1>>[NH:8]1[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][O:29][C:30]2[CH:31]=[CH:32][C:33]([C:36]([CH:38]3[CH2:39][CH2:40][CH2:41][CH2:42][CH2:43]3)=[O:37])=[CH:34][CH:35]=2)[N:10]=[CH:9]1

Participants

3

Reactant 2

HCID 108328403-(1-Trityl-1H-imidazol-4-YL)propan-1-OLHCID 12299666HCID 12299666, compound

Product 1

HCID 178519717HCID 178519717, compound

Procedure

5 mmol of 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanol and 6 mmol of cyclohexyl 4-hydroxyphenyl ketone are treated as described in Example 76.

Sources & evidence

ORD record
ord-ab8b02ea7fbc436e894c02f529c3ed2e
Source dataset
uspto-grants-2001_06
Patent number
US06248765B1

Reaction notes

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