4-Fluoro-4'-hydroxybenzophenone → HCID 178519616, compound

HRID 1067691Notes

Reaction equation

HRID 1067691 reaction equation
C1(C(C2C=CC=CC=2)(C2C=CC=CC=2)[N:8]2[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15]O)[N:10]=[CH:9]2)C=CC=CC=1.[F:29][C:30]1[CH:44]=[CH:43][C:33]([C:34]([C:36]2[CH:41]=[CH:40][C:39]([OH:42])=[CH:38][CH:37]=2)=[O:35])=[CH:32][CH:31]=1>>[F:29][C:30]1[CH:44]=[CH:43][C:33]([C:34]([C:36]2[CH:41]=[CH:40][C:39]([O:42][CH2:15][CH2:14][CH2:13][C:11]3[N:10]=[CH:9][NH:8][CH:12]=3)=[CH:38][CH:37]=2)=[O:35])=[CH:32][CH:31]=1

Participants

3

Reactant 2

HCID 1176664-Fluoro-4'-hydroxybenzophenoneHCID 108328403-(1-Trityl-1H-imidazol-4-YL)propan-1-OL

Product 1

HCID 178519616HCID 178519616, compound

Procedure

5 mmol of 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanol and 5 mmol of 4-fluoro-4′-hydroxybenzophenone are treated as described in Example 76.

Sources & evidence

ORD record
ord-5a5482fe84bb45c28e5233df3680b45a
Source dataset
uspto-grants-2001_06
Patent number
US06248765B1

Reaction notes

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