Tert-butyl 2,2,2-trichloroethanimidate → HCID 178450446, compound

HRID 1067701Notes

Reaction equation

HRID 1067701 reaction equation
C1(C(C2C=CC=CC=2)(C2C=CC=CC=2)[N:8]2[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][OH:16])[N:10]=[CH:9]2)C=CC=CC=1.ClC(Cl)(Cl)C(=N)O[C:33]([CH3:36])([CH3:35])[CH3:34]>>[NH:8]1[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][O:16][C:33]([CH3:36])([CH3:35])[CH3:34])[N:10]=[CH:9]1

Participants

3

Reactant 2

HCID 2734700Tert-butyl 2,2,2-trichloroethanimidateHCID 108328403-(1-Trityl-1H-imidazol-4-YL)propan-1-OL

Product 1

HCID 178450446HCID 178450446, compound

Procedure

5 mmol of 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanol and 10 mmol of tert-butyl trichloroacetimidate are treated as described in Example 116. The title compound is crystallized in the form of the hydrogen maleate in ethanol and diethyl ether.

Workup

  1. customThe title compound is crystallized in the form of the hydrogen maleate in ethanol and diethyl ether

Sources & evidence

ORD record
ord-af58058898454adbb365edc9c8f78cfa
Source dataset
uspto-grants-2001_06
Patent number
US06248765B1

Reaction notes

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