Benzyl 4-hydroxyphenyl ketone → HCID 178520207, compound

HRID 1067717Notes

Reaction equation

HRID 1067717 reaction equation
C1(C(C2C=CC=CC=2)(C2C=CC=CC=2)[N:8]2[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15]O)[N:10]=[CH:9]2)C=CC=CC=1.[OH:29][C:30]1[CH:35]=[CH:34][C:33]([C:36](=[O:44])[CH2:37][C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)=[CH:32][CH:31]=1>>[NH:8]1[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][O:29][C:30]2[CH:31]=[CH:32][C:33]([C:36](=[O:44])[CH2:37][C:38]3[CH:39]=[CH:40][CH:41]=[CH:42][CH:43]=3)=[CH:34][CH:35]=2)[N:10]=[CH:9]1

Participants

3

Reactant 2

HCID 75607Benzyl 4-hydroxyphenyl ketoneHCID 108328403-(1-Trityl-1H-imidazol-4-YL)propan-1-OL

Product 1

HCID 178520207HCID 178520207, compound

Procedure

5 mmol of 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanol and 6 mmol of (4-hydroxyphenyl)-2-phenylethanone are treated as described in Example 56, but crystallized in the form of hydrogen oxalate from diethyl ether and ethanol.

Workup

  1. customcrystallized in the form of hydrogen oxalate from diethyl ether and ethanol

Sources & evidence

ORD record
ord-213cd05a01a44ef6bb3f12fd6220cda0
Source dataset
uspto-grants-2001_06
Patent number
US06248765B1

Reaction notes

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