3-(1-Trityl-1H-imidazol-4-YL)propan-1-OL → HCID 178420890, compound

HRID 1067727Notes

Reaction equation

HRID 1067727 reaction equation
C1(C(C2C=CC=CC=2)(C2C=CC=CC=2)[N:8]2[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][OH:16])[N:10]=[CH:9]2)C=CC=CC=1.[Cl-].[CH:30]1([CH2:33][Na])[CH2:32][CH2:31]1>>[NH:8]1[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][O:16][CH2:33][CH:30]2[CH2:32][CH2:31]2)[N:10]=[CH:9]1

Participants

3

Reactant 2

HCID 108328403-(1-Trityl-1H-imidazol-4-YL)propan-1-OLHCID 178479011HCID 178479011, compound

Product 1

HCID 178420890HCID 178420890, compound

Procedure

5 mmol of 3-(1-triphenylmethyl-1H-imidazol-4-yl)propanol and 10 mmol of cyclopropylmethylsodium chloride are treated as described in Example 5. The title compound is crystallized in the form of hydrogen maleate from ethanol and diethyl ether.

Workup

  1. customThe title compound is crystallized in the form of hydrogen maleate from ethanol and diethyl ether

Sources & evidence

ORD record
ord-4ae5e7fb56a44364bd8cf923a85cf5a8
Source dataset
uspto-grants-2001_06
Patent number
US06248765B1

Reaction notes

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