HCID 15518070, compound → HCID 10222392, compound

Participants

Reaction Steps

A solution of the acetate of Example 25 (36 mg, 0.055 mmol) and PPTs (2 mg) in MeOH (1.0 mL) was stirred at 45° C. for 4 h. The reaction was cooled to room temperature and the solvent was removed in vacuo. The residue was diluted with EtOAc and washed with 1N HCl, saturated aqueous NaHCO3 and brine. The organic portion was dried (MgSO4), filtered and concentrated it vacuo. FCC (silica gel, 50%-100% EtOAc/hex) afforded 18 mg of the named compound.

Provenance & Evidence