HuagongsheHuagongshe Chemistry Print Report · For research reference only
Guanidine Hydrochloride → HCID 178485158, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Guanidine Hydrochloride | HCID 5742 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | Ethyl 4-acetamido-1-methyl-2-indolecarboxylate | HCID 21194389 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178485158 | HCID 178485158 | 69% |
Reaction Steps
The reaction was carried out in a manner similar to Example 1 except for using 1.40 g (5.38 mmol) of ethyl 4-acetamido-1-methyl-2-indole-carboxylate, 5.14 g (53.8 mmol) of guanidine hydrochloride and 50 ml of a methanol solution of 2.91 g (53.8 mmol) of sodium methoxide. Thus 1.15 g (69.0%) of 4-acetamido-1-methyl-2-indoloylguanidine hydrochloride was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06248772B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-1bea29396df34b61a920b948a7286744 |
| Source note | uspto-grants-2001_06 |