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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1067809Generated: October 30, 2026

Guanidine Hydrochloride → HCID 178479357, compound

https://huagongshe.com/reaction/1067809

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGuanidine HydrochlorideHCID 5742—
ReactantSodium MethoxideHCID 10942334—
ReactantHCID 21194070HCID 21194070—
SolventMethanolHCID 887—
ProductHCID 178479357HCID 178479357—

Reaction Steps

The reaction was carried out in a manner similar to Example 1 except for using 1.00 g (5.23 mmol) of methyl 1-hydroxy-2-indolecarboxylate, 5.00 g (52.3 mmol) of guanidine hydrochloride and 50 ml of a methanol solution of 2.82 g (52.3 mmol) of sodium methoxide. 1-Hydroxy-2-indoloylguanidine hydrochloride was obtained in an amount of 0.56 g (42.0%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06248772B1
Source datasetuspto-grants-2001_06
ORD IDord-8da0846d5ea5452e9ceafd7cd6993668
Source noteuspto-grants-2001_06