Hexane → HCID 21192603, compound

Participants

Reaction Steps

A solution of ethyl 8-fluoro-6-iodo-1-methyl-4-oxo-1,4-dihydro-3-quinolinecarboxylate from Preparation No. 13 (15.8 g) in p-chlorobenzylarnine (15.4 mL) is warmed to 190° C. The mixture is then cooled to room temperature, and hexane is added. The resulting precipitate is collected by filtration to give the title compound as a solid. An analytical sample is prepared by recrystallization from EtOH.

Provenance & Evidence