Trifluoroacetic acid → HCID 10791549, compound

Participants

Reaction Steps

According to the method described for the preparation of 17a, 16b (78 mg, 0.12 mmol) was reacted with trifluoroacetic acid (704 mg, 6.20 mmol) and triethylsilane (140 mg, 11.92 mmol) in CH2Cl2 (0.98 mL) to give 17b (37 mg, 62%) as a colorless oil: 1H NMR δ 1.20-2.10 (m, 8H), 3.05-3.70 (m, 7H), 3.82 (m, 1H), 5.05 (s, 2H), 5.10 (s, 2H), 7.20-7.60 (m, 10H); HRMS m/z calcd for C26H36N3O7 502.2553, found 502.2546. [α]23D+3.6° (c 1.00, CH3OH).

Provenance & Evidence