Hydrochloric Acid → 3-(1-Benzylpiperidin-4-yl)-3H-imidazo[4,5-b]pyridine

Participants

Reaction Steps

The title compound was prepared from 153 mg of 2-N-(1-benzyl-piperidin-4-yl)-pyridine-2,3-diamine (from Step B), 6 mL of trimethyl orthoformate, and) 0.2 mL of concentrated HCl, using a procedure analogous to that described in Example 95, Step B to provide 139 mg of the title compound as a yellow solid.

Provenance & Evidence