HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium formate → 3-(Piperidin-4-yl)-3H-imidazo[4,5-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium formate | HCID 2723923 | — |
| Reactant | 3-(1-Benzylpiperidin-4-yl)-3H-imidazo[4,5-b]pyridine | HCID 20955395 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(Piperidin-4-yl)-3H-imidazo[4,5-b]pyridine | HCID 11447011 | 95.6% |
Reaction Steps
The title compound was prepared from 130 mg of 3-(1-benzyl-piperidin-4-yl)-3-H-imidazo[4,5-b]pyridine (from Step C), 130 mg of 10% palladium on carbon and 130 mg of ammonium formate in 6 mL of MeOH, using a procedure analogous to that described in Example 95, Step C to provide 86 mg of the title compound as a solid
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06248755B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-18b7a52b906441aca7b7b0dcfa66d8af |
| Source note | uspto-grants-2001_06 |