HCID 21193082, compound → HCID 131722698, compound

Participants

Reaction Steps

The title compound (36 mg) was prepared by reductive amination of 31 mg of α-(R)-(3-(R)-formyl-4-(S)-phenylpyrrolidin-1-yl)- cyclohexaneacetic acid, 4-methoxybenzyl ester (prepared above as Aldehyde 5) with 22 mg of 4-(8,9-dihydro-7H-5-oxa-7-aza-benzocyclo-hepten-6-one-7-yl)-piperidine hydrochloride according to the procedure of Example 1, step D. 1H NMR (500MHz, CDCl3): δ0.9-1.3 (m, 5H), 1.5-2.0 (m, 12H), 2.25-3.3 (m, 13H), 3.63 (m, 2H), 3.82 (s, 3H), 3.96 (m, 1H), 5.13 (ABq, 2H), 6.9-7.4 (m, 13H).

Provenance & Evidence