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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1068229Generated: October 31, 2026

2-Aminopyridine → 2-Ethylimidazo[1,2-a]pyridine

https://huagongshe.com/reaction/1068229

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminopyridineHCID 10439—
Reactant1-Bromo-2-butanoneHCID 13156—
Product2-Ethylimidazo[1,2-a]pyridineHCID 21831991—

Reaction Steps

The title compound was prepared from 2-aminopyridine and 1-bromo-2-butanone, employng procedures analogous to those described in Example 235, Step A. 1H NMR (500 MHz, CDCl3): δ 1.34 (t, J=7.3 Hz, 3H), 2.82 (q, J=7.6Hz, 2H), 6.70 (t, J=6.6 Hz, 1H), 7.10 (m, 1H), 7.32 (s, 3H), 7.51 (d, J=8.9 Hz, 1H), 8.03 (dd, J=6.6, 0.9 Hz, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06248755B1
Source datasetuspto-grants-2001_06
ORD IDord-72d185566cf046a3b50d10320c56f09a
Source noteuspto-grants-2001_06